The NALM-6 mannequin, a helpful device in preclinical leukemia analysis, entails the implantation of human acute lymphoblastic leukemia cells into immunodeficient mice. This creates a residing system that mirrors the development and response to remedy seen in human leukemia, permitting researchers to review the illness and check potential therapies in a extra managed setting.
This mannequin’s growth supplied researchers with a essential platform for testing new therapies and finding out leukemia growth. It permits for detailed evaluation of illness development, drug resistance mechanisms, and the interplay between leukemia cells and the microenvironment. The power to check potential therapies in vivo earlier than scientific trials provides a extra environment friendly and moral strategy to drug growth, contributing to the development of leukemia therapy.
